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Research

Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism

We examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection.

Research

Detecting genotyping error using measures of degree of Hardy-Weinberg disequilibrium - art. no. 5

Tests for Hardy-Weinberg equilibrium (HWE) have been used to detect genotyping error, but those tests have low power unless the sample size is very large.

Research

Prenatal stress and risk of behavioral morbidity from age 2 to 14 years:

The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development offspring...

Research

Free testosterone levels in umbilical-cord blood predict infant head circumference in females

Fetal androgens influence fetal growth as well as postnatal neurocognitive ability

Research

Association between socioeconomic status and the development of asthma: analyses of income trajectories

Using data on 2868 children born in the Western Australian Pregnancy Cohort (Raine) Study, we examined the association between changes in family...

Research

An open letter to politicians on climate change and obesity

An open letter to politicians on climate change and obesity

Research

Th2-polarisation of cellular immune memory to neonatal pertussis vaccination

Current infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular...

Research

Fortification of flour with folic acid

After randomized, controlled trials established that consumption of folic acid before pregnancy and during the early weeks of gestation reduces the risk...

Research

A systematic review of the importance of milk TGF-β on immunological outcomes in the infant and young child

Cytokines in milk like transforming growth factor-beta (TGF-beta) have been shown to induce oral tolerance in experimental animal studies