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Research

Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

The antirelapse efficacy of primaquine is related to the total dose administered, whereas the risks of haemolysis and gastrointestinal intolerance are associated with the daily dose administered. National Malaria Control Programmes require local information on efficacy, tolerability and safety to optimize antimalarial treatment policies for Plasmodium vivax malaria control and elimination efforts.

Research

A New Era for PPARγ: Covalent Ligands and Therapeutic Applications

Peroxisome proliferator-activated receptor γ (PPARγ) is a prominent ligand-inducible transcription factor involved in adipocyte differentiation, glucose homeostasis, insulin sensitivity, inflammation, and cell proliferation, making it a therapeutic target for diabetes, metabolic syndrome, autoimmune diseases, and cancer. 

Research

Non-Suicidal Self-Injury and Outcome Expectancies: The Roles of Self-Efficacy, Cognitive Reappraisal, and Expressive Suppression

According to the Cognitive Emotional Model of Non-Suicidal Self-Injury (NSSI), this behavior is governed by a complex interplay of NSSI-related cognitions (i.e., a person's expected outcomes of self-injury and self-efficacy to resist NSSI) and emotion-regulatory strategies (i.e., cognitive reappraisal and expressive suppression). To empirically test this proposition, the current study examined the moderating roles of self-efficacy to resist NSSI, cognitive reappraisal, and expressive suppression in the relationships between outcome expectancies and NSSI frequency among university students.

Research

Tourette Syndrome

Occurring in 1% of school-aged children, Tourette syndrome is a neurodevelopmental disorder characterised by uncontrollable movements and vocalisations known as tics.

Research

Meningitis

Meningitis is when the membranes that surround the brain and spinal cord (meninges) become infected by the bacteria Neisseria meningitidis.

Impact: Research Translation

On this Research Impact page, learn about our work that's actively translated as Government policy or in active practice. Learn how our research is making a difference in people's lives - not tomorrow, next week, or next year - but today!

Ambitious flu program aims to protect kids for life

A bold research program is working to give young children lifelong protection against influenza

RSV: The Hidden Virus

Despite respiratory syncytial virus (RSV) being the leading cause of hospitalisations in the first year of life, there is currently no routine preventative option for otherwise healthy babies.

‘Boom Boom’ goes the beat towards ending rheumatic heart disease

A song written by kids in Barunga as part of the END RHD Communities Project is helping prevent the spread of infections that cause rheumatic heart disease in remote Aboriginal Communities.

RESP-ACT

The aim of RESP-ACT is to reduce these children’s respiratory hospital admissions and visits to Emergency Department, and to help them and their families to have as the best possible quality of life.