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An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solutionTyphoid fever is a major global health problem, the control of which is hindered by lack of a suitable animal model in which to study Salmonella Typhi...
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Prospective associations between dietary patterns and cognitive performance during adolescenceHigher dietary intake of the 'Western' dietary pattern at age 14 is associated with diminished cognitive performance 3 years later, at 17 years.
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The right interventions for each child with cerebral palsyThis paper is a comment on an article published in a previous edition of the journal on a clinical intervention strategy for children with cerebral palsy.
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Adjusting for under-identification of Aboriginal and/or Torres Strait Islander births in time series produced from birth recordsStatistical time series derived from administrative data sets form key indicators in measuring progress.
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Wound healing genes and susceptibility to cutaneous leishmaniasis in BrazilLeishmania braziliensis causes cutaneous (CL) and mucosal (ML) leishmaniasis. In the mouse, Fli1 was identified as a gene influencing enhanced wound healing...
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Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's diseaseGenome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits...
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Respiratory viral pathogens associated with lower respiratory tract disease among young childrenAcute lower respiratory tract infections (ALRI) commonly result in fatal outcomes in the young children of Papua New Guinea (PNG).
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Impact of the Reelin signaling cascade (Ligands-Receptors-Adaptor Complex) on cognition in schizophreniaOur previous neurocognitive studies of schizophrenia outlined two clusters of affected subjects-cognitively spared (CS) and cognitive deficit (CD), the...
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Clarithromycin therapy for patients with Cystic Fibrosis: A randomized controlled trialThe clinically significant actions of oral azithromycin in modifying progressive cystic fibrosis (CF) lung disease have been well documented.
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Genetic variants in ER cofactor genes and endometrial cancer riskGiven that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER...