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Research

Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC

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Increased Use of Adrenaline in the Management of Childhood Anaphylaxis Over the Last Decade

There was a significant improvement in the management of anaphylaxis after the introduction of intensified physician training programs

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Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models

This JAK3A572V knockin model is a relevant new tool for testing the efficacy of JAK inhibitors in JAK3-related hematopoietic malignancies

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Respiratory function in healthy Emirati children using forced oscillations

Forced oscillation technique measurements were feasible in Emirati school-children. New forced oscillation technique reference equation in Emirati children were derived.

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Elucidating the genetic architecture of Adams-Oliver syndrome in a large European cohort

The purpose of this study was therefore to comprehensively examine the genetic architecture of Adams-Oliver syndrome in an extensive cohort

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Navigating 'the system' to find supports and services for people with developmental disability: How can research help make this a better journey?

Parents navigate what can be a confusing world of early intervention services, residing in the health, disability and/or education sectors

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Cohort Profile: The New South Wales Child Development Study (NSW-CDS)-Wave 2 (child age 13 years)

The New South Wales Child Development Study was established to enable a life course epidemiological approach to identifying risk and protective factors

Research

Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis

Our data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans

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The influence of incomplete case ascertainment on measures of vaccine efficacy

A biologically active vaccine may produce a low measured vaccine efficacy under a range of epidemiological, vaccine-related and logistical conditions

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Parent-reported health-related quality of life of children with Down syndrome: A descriptive study

To describe health-related quality of life of Australian children and adolescents with Down syndrome and compare it with norm-referenced data.