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Reports and Findings

Research

Improving Health Outcomes in the Tropical North: A Multidisciplinary Collaboration (HOT NORTH)

‘Improving Health Outcomes in the Tropical North’ will strengthen partnerships with key research institutions across the NT, Qld, WA, NSW, Vic and SA, by undertaking an integrated research agenda that will help close the gap in Indigenous health disadvantage, protect the north from emerging infectious threats and

Research

Development of a longer acting formulation of Penicillin G for the treatment and prevention of acute rheumatic fever and rheumatic heart disease

This project aims to develop a longer acting formulation of penicillin, such that frequency of the injection can be increased up to 3-6 months.

Research

The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis.

Research

Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

Recruitment of large numbers of pediatric pneumonia and meningitis cases and community controls in a third-world setting presents unique challenges

Research

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria.

Research

Maternal dietary intake in pregnancy and lactation and allergic disease outcomes in offspring

As the prevalence of allergic disease dramatically rises worldwide, prevention strategies are increasingly being considered.

Research

Comparison of outcomes following a cytological or histological diagnosis of malignant mesothelioma

This study examines survival differences between patients with epithelioid MM diagnosed by cytology only and other subtypes diagnosed by histology.

Research

Chest imaging in cystic fibrosis studies: What counts, and can be counted?

The aim of this study is to characterize the role of currently available CT and MRI markers in clinical studies, and to discuss challenges with CF studies.