Reports and Findings
Research
Centre for Advanced Cancer Genomics (CACG)Current technologies to understand which genes are turned on or off only work on large amounts of biological samples. As a consequence all measurements we receive represent averages across multiple cell types present in the sample. The situation is comparable to studying the contents of a bowl of fr
Research
Undiagnosed Diseases Program (UDP) and Bringing the benefits of precision medicine to children in Western AustraliaWe have started a project utilising whole genome sequencing of undiagnosed children living in WA to provide a definitive diagnosis. A major challenge here is that the role and functions of the inter-genic regions of our genome (the remaining 98%) are relatively poorly understood.
Research
Does commencement of a gluten- free diet improve blood glucose control in children and young people with Type 1 Diabetes and Coeliac Disease?If the gut becomes damaged it may not be able to process the foods that we eat as well as it used to. This may also affect how we look after diabetes.
Research
Understanding Diabetes: Early environmental determinants of pancreatic islet autoimmunity: a pregnancy to early life cohort study in children at risk of type 1 diabetesThis study is looking for the causes of type 1 diabetes, so that we can find ways to prevent it. We will follow many women around Australia during pregnancy until early childhood, looking at the child's birth, environment and genes.
Research
Exercising Safely with Type 1 Diabetes – Development of Clinical GuidelinesOur research focuses on what are the best ways for patients with Type 1 Diabetes to exercise safely. We aim to develop clinical guidelines that provide improved advice for patients and educate patients on how to prevent hypos during and after exercise.
Research
Use of Hybrid Closed Loop therapy in hypoglycaemia awarenessThis study will tell us if the use of a hybrid closed loop system can improve awareness of hypoglycaemia.
Research
National Hybrid Closed-Loop Outpatient TrialThe national Hybrid Closed-Loop Outpatient Trial will test the use of an automated insulin delivery system to see if it is better at optimising blood glucose levels than standard therapy.
Research
Penicillin ProgramOur program of work has the ultimate aims of improving quality, supply and acceptability of existing formulations of BPG, and of developing a novel long-acting penicillin formulation.
Research
National Healthy Skin Guideline: For the Prevention, Treatment and Public Health Control of Impetigo, Scabies, Crusted Scabies and Tinea for Indigenous Populations and Communities in AustraliaA clinical guideline that provides a detailed discussion of the evidence for treatment of skin infections in resource poor settings.
Research
ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testingAssessment of airway hyperresponsiveness are valuable tools to understand and to monitor airway function and to characterise the underlying asthma phenotype to guide therapy