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Research

Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis

Coxiella burnetii is a Gram-negative intracellular pathogen that causes the debilitating disease Q fever, which affects both animals and humans. The only available human vaccine, Q-Vax, is effective but has a high risk of severe adverse reactions, limiting its use as a countermeasure to contain outbreaks. Therefore, it is essential to identify new drug targets to treat this infection.

News & Events

The Kids ‘Tall Poppies’ rise above the rest

Three The Kids researchers have been named amongst WA’s most outstanding young scientists for their efforts to ensure kids around the country have the chance to lead happy and healthy lives.

News & Events

New ear health study music to the ears of Aboriginal children

Wait times for Aboriginal children suffering ear infections could be reduced to less than four weeks thanks to a new The Kids Research Institute Australia research project

News & Events

$3.4mill to improve treatment management of cystic fibrosis

The Kids researchers have been awarded over $3.4 million for a new trial to pioneer improved ways for managing cystic fibrosis (‘CF’).

News & Events

Bill & Melinda Gates Foundation Grant aims to prevent deadly infections in early life

Newborn babies and their fragile immune systems struggle to fight off nasty infections such as septicaemia, pneumonia and gastroenteritis.

Research

More than dirt: Sedimentary ancient DNA and Indigenous Australia

The rise of sedimentary ancient DNA (sedaDNA) studies has opened new possibilities for studying past environments. This groundbreaking area of genomics uses sediments to identify organisms, even in cases where macroscopic remains no longer exist. Managing this substrate in Indigenous Australian contexts, however, requires special considerations. Sediments and soils are often considered as waste by-products during archaeological and paleontological excavations and are not typically regulated by the same ethics guidelines utilised in mainstream 'western' research paradigms.

Research

Pneumococcal carriage, serotype distribution, and antimicrobial susceptibility in Papua New Guinean children vaccinated with PCV10 or PCV13 in a head-to-head trial

Children in Papua New Guinea (PNG) are at high risk of pneumococcal infections. We investigated pneumococcal carriage rates, serotype distribution, and antimicrobial susceptibility in PNG children after vaccination with 10-valent or 13-valent pneumococcal conjugate vaccines (PCV10; PCV13).

Elegant mathematical tool could spell the difference for kids globally

A powerful data tool developed by international child development researcher Professor Sally Brinkman and former research assistant Tom Brown could improve early childhood support for children around the world after being launched in Dubai this year.

Helping communities take charge of the early years

A program unfolding in four very diverse locations across Western Australia is working to give children aged 0–4 the best start in life.

A hop, skip and a jump to better health for kids

Not too long ago, if you had mentioned physical activity to educators at the Sonas Early Learning & Care centres run by Shelley Prendergast, they would automatically have reached for the trusty old obstacle course.