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Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteinsPhylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited
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ANRIL Promoter DNA Methylation: A Perinatal Marker for Later AdiposityExperimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes.
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Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsinIdentified romidepsin as a promising therapeutic for mixed lineage leukemia (MLL)-rearranged infant acute lymphoblastic leukemia
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Evidence of a reduction over time in the behavioral severity of autistic disorder diagnosesThis study provides the first clear evidence of a reduction over time in the behavioral severity of individuals diagnosed with Autistic Disorder during a period of stability in diagnostic criteria
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Dietary Vitamin D Increases Percentages and Function of Regulatory T Cells in the Skin-Draining Lymph Nodes and Suppresses Dermal InflammationDietary vitamin D3 increased the suppressive activity of regulatory T cells in the skin-draining lymph nodes, which are poised to suppress dermal inflammation
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Short report: Relationship between restricted and repetitive behaviours in children with autism spectrum disorder and their parentsRestricted and repetitive behaviours constitute a core symptom domain of autism spectrum disorder
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Commentary: Are we expecting too much from the extreme male brain theory of autism? A reflection on Kung et al. (2016)This commentary highlights inconsistent findings that undermine the extreme male brain theory autism but data may not present an adequate test of the hypothesis
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Risk factors for repetition of a deliberate self-harm episode within seven days in adolescents and young adultsThe risk of repetition of deliberate self-harm peaks in the first 7 days after a deliberate self-harm episode.
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Cyber AgressionInformation and communication technology has allowed individuals to engage in aggressive behavior on multiple distinct platforms with different capabilities
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Temporal changes in BEXSERO® antigen sequence type associated with genetic lineages of Neisseria meningitidis over a 15-year period in Western AustraliaThe BEXSERO® vaccine which is used to prevent serogroup B disease is composed of four sub-capsular protein antigens supplemented with an outer membrane vesicle.