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Beyond bone: the emerging role of osteoclasts in immune regulation, leukemia development and following myeloablative therapyOsteoclasts are important regulators of bone remodeling, with an established role in maintaining skeletal homeostasis. The emergence of osteoimmunology has identified osteoclasts as key players in the immune system. In particular, osteoclasts can initiate bi-directional crosstalk mechanisms with hematopoietic stem cells and various immune cells, such as T cells, B cells and NK cells, to influence hematopoiesis and inflammatory response.
Registration Details about Registration When you register you will be asked to register for both the two-day auditorium presentations on days one and
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Effectiveness of nirsevimab in preventing RSV-hospitalisation among young children in Western Australia 2024Respiratory Syncytial Virus (RSV) causes a significant burden of illness for children under 2 years of age. Nirsevimab, a long-acting monoclonal antibody, was registered for RSV prevention in Australia in 2023. In April 2024, Western Australia (WA) launched the country's first state-wide nirsevimab program for all infants and high-risk children entering their second RSV season.
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The Long-term Impact of Serogroup B Invasive Meningococcal Disease (IMD) in Australian Adolescents and Young Adults: AMEND studyChristopher Peter Blyth Richmond MBBS (Hons) DCH FRACP FRCPA PhD MBBS MRCP(UK) FRACP Centre Head, Wesfarmers Centre of Vaccines and Infectious
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Strep A Vaccine Global Consortium (SAVAC) 1.0The Kids Research Institute Australia (Jonathan Carapetis) is a member of the new Global Strep A Vaccine Consortium; a global GAS vaccine consortium that will drive strategic planning to anticipate requirements for licensure, prequalification, and policy recommendations.
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The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018A significant reduction in severe influenza was observed in Australian children, possibly contributed to by improved vaccine coverage and high vaccine effectiveness
In 2020, the National Closing the Gap partnership made improving early development of Aboriginal and Torres Strait Islander children one of its top priorities. Australia will measure progress in this area using the AEDC.
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Gender DiversityNot all children or teenagers identify with the gender they were assigned at birth. As a result, some may choose to change their name, their clothes or their body. With considerably higher rates of depression, anxiety, self-harm and attempted suicide, the need for specialist mental health services has been recognised.
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Antigen reactivity defines tissue-resident memory and exhausted T cells in tumorsCD8+ T cells are an important weapon in the therapeutic armamentarium against cancer. While CD8+CD103+ T cells with a tissue-resident memory T (TRM) cell phenotype are associated with favorable prognoses, the tumor microenvironment also contains dysfunctional exhausted T (TEX) cells that exhibit a variety of TRM-like features.
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The definition of asthma remission in children: A scoping review by the WAO Paediatric Asthma CommitteeAsthma remission has emerged as a potential therapeutic goal. However, definitions of remission have primarily focused on adult populations, with limited consensus on how remission should be defined in children.
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LeukaemiaLeukaemia, also spelled leukemia, is a cancer that develops in the bone marrow and results in abnormal white blood cells. It is the most common cancer in children, accounting for almost a third of all childhood & teen cancers.
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PertussisPertussis, also known as whooping cough, is a highly contagious respiratory disease.
Time to reflect After your leadership team has completed an activity it is important to take time to reflect on how it went and things you may have
Cybersafe practices are precautions we can take to make sure our interactions online are safe and positive. Download the "My Online Status" in the
The Health Promotion and Education Research Team at The Kids Research Institute Australia received funding from the auDA Foundation to develop this