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Research

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

Our data support a highly generalizable model in which enhancer transcription is the earliest event in successive waves of transcriptional change during...

Research

The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stage

Although debate surrounding the mechanism or mechanisms governing this causal pathway remains intense, demonstration of the capacity of pretreatment...

Research

Contrasting effects of prenatal life stress on blood pressure and bodymass index in young adults

The effect of prenatal life stress on BP was accentuated by a higher BMI. Fetal programming events as a result of prenatal stress may underpin some of these...

Research

The association between autism and schizophrenia spectrum disorders: A review of eight alternate models of co-occurrence

Understanding how and why these disorders co-occur has important implications for diagnosis, treatment, and prognosis, as well as for developing fundamental...

Research

A novel technique of serial biopsy in mouse brain tumour models

Here we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model

Research

Population-based estimates of the effectiveness of pneumococcal vaccination in Australia

Australia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide.

Research

Randomized controlled trial of early regular egg intake to prevent egg allergy

We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema.

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Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

These data suggest that late gestation sex steroids do not exert a major effect on nonverbal and verbal abilities in middle childhood.

Research

International consensus (ICON) on: Clinical consequences of mite hypersensitivity, a global problem

The objectives of this document are to highlight aspects of mite biology that are clinically relevant and to update the current knowledge on mite allergens