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Research

More Than Effects in Skin: Ultraviolet Radiation-Induced Changes in Immune Cells in Human Blood

Cells of the skin and circulation are in constant two-way communication. Following exposure of humans to sunlight or to phototherapy, there are alterations in the number, phenotype and function of circulating blood cells.

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OMIP 076: High-dimensional immunophenotyping of murine T-cell, B-cell, and antibody secreting cell subsets

There is now considerable evidence demonstrating that both prenatal and postnatal exposure to particular classes of microbial stimuli can provide beneficial signals during early life immune development, resulting in the protection against future inflammatory disease.

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Large-scale open-source three-dimensional growth curves for clinical facial assessment and objective description of facial dysmorphism

Craniofacial dysmorphism is associated with thousands of genetic and environmental disorders. Delineation of salient facial characteristics can guide clinicians towards a correct clinical diagnosis and understanding the pathogenesis of the disorder. Abnormal facial shape might require craniofacial surgical intervention, with the restoration of normal shape an important surgical outcome.

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Burden and preference-based quality of life associated with bullying in children

The objectives of this study are to assess the association between childhood bullying and preference-based health-related quality of life in Australian school children and their parents and estimate quality-adjusted life years associated with bullying chronicity. Children aged 8-10 years completed the child health utilities, while parents completed the Australian quality of life.

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Exploring stakeholders' perceptions of the acceptability, usability, and dissemination of the australian 24-hour movement guidelines for the early years

This study examined stakeholders' perceptions regarding the acceptability, usability, and dissemination of the Australian 24-Hour Movement Guidelines

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Hypospadias Prevalence and Trends in International Birth Defect Surveillance Systems, 1980–2010

We report on the prevalence and trends of hypospadias which indicate that the prevalence of hypospadias continues to increase internationally

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Systems biology and big data in asthma and allergy: recent discoveries and emerging challenges

We describe recent "omic"-level findings, and examine how these findings have been systematically integrated to generate further insight

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Effects of UVR exposure on the gut microbiota of mice and humans

Both human and murine studies report that multiple exposures to sub-erythemal UV radiation can increase the diversity of the gut microbiome

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Sun exposure: An environmental preventer of metabolic dysfunction?

Emerging preclinical findings suggest that some sun exposure is necessary for optimal metabolic health

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Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex

Infants with Tuberous sclerosis complex demonstrated reduced interhemispheric alpha phase coherence compared to controls at 12 months of age