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New study uncovers dual benefit of bone-protecting treatment for childhood leukaemiaA groundbreaking study from cancer researchers at The Kids Research Institute Australia has identified a promising new therapeutic strategy for children battling the most common childhood cancer – B-cell acute lymphoblastic leukaemia.
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Nasal Delivery of Haemophilus haemolyticus Is Safe, Reduces Influenza Severity, and Prevents Development of Otitis Media in MiceDespite vaccination, influenza and otitis media (OM) remain leading causes of illness. We previously found that the human respiratory commensal Haemophilus haemolyticus prevents bacterial infection in vitro and that the related murine commensal Muribacter muris delays OM development in mice. The observation that M muris pretreatment reduced lung influenza titer and inflammation suggests that these bacteria could be exploited for protection against influenza/OM.
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Evaluation of a bacterial therapy for prevention of respiratory infection including influenza and otitis mediaDeborah Lea-Ann Peter Ruth Strickland Kirkham Richmond Thornton PhD PhD MBBS MRCP(UK) FRACP PhD Head, Pregnancy and Early Life Immunology Co-Head,
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The mark of success: The role of vaccine-induced skin scar formation for BCG and smallpox vaccine-associated clinical benefitsSkin scar formation following Bacille Calmette-Guérin (BCG) or smallpox (Vaccinia) vaccination is an established marker of successful vaccination and 'vaccine take'. Potent pathogen-specific (tuberculosis; smallpox) and pathogen-agnostic (protection from diseases unrelated to the intentionally targeted pathogen) effects of BCG and smallpox vaccines hold significant translational potential.
News & Events
Pitch perfect projects powered by philanthropyEarlier this week ten emerging researchers took to the stage to pitch their projects to a room full of excited and engaged philanthropists who share our vision of happy, healthy kids.
Our team uses AI to quickly analyse large amounts of genetic data to help discover alternate medications and improve existing treatments.
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Improving Wellbeing for Young People Living with Rheumatic Heart Disease: A peer support program through Danila Dilba Health ServiceThis project seeks to conduct a focus group for young people (aged 11-14) and their parents/family members through the Danila Dilba Health Service (DDHS) in Darwin with the aim of identifying consumer needs and perspectives on next steps and priorities for peer support in RHD.
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Development of a longer acting formulation of Penicillin G for the treatment and prevention of acute rheumatic fever and rheumatic heart diseaseThis project aims to develop a longer acting formulation of penicillin, such that frequency of the injection can be increased up to 3-6 months.
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BPG Formulation Preferences Study: Exploring patient, family and clinician reformulations preferences for BPGThe key objective of this study is to collect data about patient and clinician preferences about reformulations.
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Factors associated with pneumococcal carriage and density in children and adults in Fiji, using four cross-sectional surveysThis study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji