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Research

Intersex adolescents seeking help for their depression: the case study of SPARX in New Zealand

SPARX is a computerized cognitive behavioral therapy self-help program for adolescent depression that is freely available in New Zealand. At registration, users identify themselves as either male, female, intersex, or transgender. We aimed to describe the mental health of adolescent intersex users. A secondary analysis of SPARX usage data over 5 years.

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Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

Epigenetics links perinatal influences with later obesity. We identifed differentially methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity measures and examined whether these were associated with hsCRP, adipokines, and early life environmental factors. Genome-wide DNA methylation from 1192 Raine Study participants at 17 years, identified 29 dmCpGs associated with body mass index, 10 with waist circumference and 9 with subcutaneous fat thickness.

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Fetal alcohol spectrum disorder and the criminal justice system

Fetal Alcohol Spectrum Disorder (FASD) is a condition caused by prenatal exposure to alcohol and characterised by severe neurodevelopmental impairment which have lifelong implications. Impairments in executive function, memory, cognition, language and attention are common, and can lead to early and repeat engagement with the criminal justice system.

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Childhood vaccination and allergy: A systematic review and meta-analysis

As the rise in prevalence of allergic diseases worldwide corresponds in time with increasing infant vaccination, it has been hypothesized that childhood vaccination may increase the risk of allergic disease. We aimed to synthesize the literature on the association between childhood vaccination and allergy.

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Suicide by young Australians, 2006-2015: a cross-sectional analysis of national coronial data

Citation: Hill NTM, McGorry PD, Robinson J. Suicide by young Australians, 2006–2015: a cross-sectional analysis of national coronial data. Med J Aust

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Bacterial Reservoirs in the Middle Ear of Otitis-prone Children Are Associated With Repeat Ventilation Tube Insertion

Presence of bacterial otopathogen in the middle ear during ventilation tube insertion was a predictor of children at-risk of repeat ventilation tube insertion

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Panel 7 – Pathogenesis of otitis media – A review of the literature between 2015 and 2019

The most urgent areas appear to be to continue monitoring the emergence of novel otopathogens, and the need to develop prevention and preventative therapies

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Macroeconomic Fluctuations in Home Countries and Immigrants’ Well-Being: New Evidence from Down Under

Our findings suggest that immigrants in Australia have emotional or altruistic connections to their home countries

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Modelling factors for Aboriginal and Torres Strait Islander child neurodevelopment outcomes: A latent class analysis

This study highlights a range of unique profiles that can be used for improving the early development of young Aboriginal children

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Genetic Manipulation of Group A Streptococcus-Gene Deletion by Allelic Replacement

An optimized, rapid method for creating markerless isogenic mutations that combines Gibson assembly cloning with a new temperature-sensitive plasmid, pLZts