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Research

Impact of CD14 promoter variants on measles vaccine responses and vaccine failure in children from Australia and Mozambique

Host genetics are likely to play a crucial role, particularly variants that alter key innate immune response genes.

Research

Prevention of rheumatic fever and heart disease: Nepalese experience

Historically, many young people suffered severe valvular disease and died awaiting heart valve replacement.

Research

The impact of interventions to promote physical activity in urban green space: A systematic review and recommendations for future research

A systematic review was undertaken to assess the effectiveness of interventions to encourage physical activity in urban green space.

Research

Childhood adiposity trajectories and risk of nonalcoholic fatty liver disease in adolescents

Nonalcoholic fatty liver disease and its metabolic risk factors are recognized during childhood and adolescence.

Research

Dendritic cells and influenza A virus infection

Influenza A virus (IAV) is a dangerous virus equipped with the potential to evoke widespread pandemic disease.

Research

Comparison of neonatal T regulatory cell function in Papua New Guinean and Australian newborns

We compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New Guinea)...

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Vitamin D 3 deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway disease

In this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.

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Inert 50-nm Polystyrene Nanoparticles That Modify Pulmonary Dendritic Cell Function and Inhibit Allergic Airway Inflammation

Nanoparticles are being developed for diverse biomedical applications, but there is concern about potential to promote inflammation, particularly in the lungs.

Research

Child maltreatment: variation in trends and policies in six developed countries

We explored trends in six developed countries in three types of indicators of child maltreatment for children younger than 11 years.