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Research

Adolescent perceptions of bystanders’ responses to cyberbullying

This study explored the perceptions of, and key influences on, adolescent bystanders who witness cyberbullying

Research

Qualitative Analysis of Parental Observations on Quality of Life in Australian Children with Down Syndrome

We investigated parental observations to identify QOL domains in children with Down Syndrome and determined whether domains differed between children and teens.

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The Importance of Scabies Co-Infection in the Treatment Considerations for Impetigo

Treatment success for scabies co-infection was lower than for impetigo overall, with a higher success seen in the co-trimoxazole group than benzylpenicillin

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Respiratory viruses in young South African children with acute lower respiratory infections and interactions with HIV

RV-A and RV-C are endemic in South African children and HIV infection may be protective against RSV and bronchiolitis.

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Knowledge translation lessons from an audit of Aboriginal Australians with acute coronary syndrome presenting to a regional hospital

This audit is used as a case study of translating knowledge processes in order to identify the factors that support equity-oriented knowledge translation.

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Gross motor performance in children prenatally exposed to alcohol and living in remote Australia

A higher than expected proportion of children with fetal alcohol spectrum disorders had gross motor scores that indicated impairment and need for therapy

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Lipidomics reveals associations of phospholipids with obesity and insulin resistance in young adults

Lipidomic biomarkers associated with obesity and IR using plasma samples from a population-based cohort of young adults

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Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans

Our data demonstrate a causal relationship between activating Pik3ca mutations and the genesis of venous malformations

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Reduced heart rate variability in remitted bipolar disorder and recurrent depression

Heart Rate Variability was found to be lower in the bipolar and depression groups, compared with control subjects

Research

The potential of antisense oligonucleotide therapies for inherited childhood lung diseases

Antisense oligonucleotides are an emerging therapeutic option to treat diseases with known genetic origin. In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing. Antisense oligonucleotides can alter gene expression through a variety of mechanisms as determined by the chemistry and antisense oligomer design.