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Antibody persistence and booster response in adolescents and young adults 4 and 7.5 years after immunization with 4CMenB vaccineA more robust immune response after booster compared to a first dose in vaccine-naïve individuals, showed effective priming in an adolescent/young adult population
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Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute WheezingAsthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes
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Online self-compassion training to improve the wellbeing of youth with chronic medical conditions: Protocol for a randomised control trialThe Self-Compassion Online program could provide a scalable solution for improving psychological outcomes and quality of life among youth with chronic illness
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An integrative analysis of non-coding regulatory DNA variations associated with autism spectrum disorderOverall, we found that the regulatory variants in autism spectrum disorder cases were enriched in ASD-risk genes and genes involved in fetal neurodevelopment
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Bronchopulmonary dysplasia: Rationale for a pathophysiological rather than treatment based approach to diagnosisThis review describes the evolution of bronchopulmonary dysplasia definitions, evaluates the benefits and limitations of each approach
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Eighth annual conference of in VIVO planetary health: From challenges to opportunitiesHere, we present the abstracts and proceedings of our 8th annual conference, held in Detroit, Michigan in May 2019, themed "From Challenges, to Opportunities"
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Priorities for improved management of acute rheumatic fever and rheumatic heart diseaseThe results suggest that timely injection and patient education are priorities for managing ARF and RHD, particularly focusing on child-to-adult transition care.
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Changing Prevalence of Lower Airway Infections in Young Children with Cystic FibrosisAspergillus species and P. aeruginosa are commonly present in the lower airways from infancy
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Molecular Epidemiology of Noninvasive and Invasive Group A Streptococcal Infections in Cape TownThere is low coverage of the multivalent M protein vaccine in our setting, emphasizing the need to reformulate the vaccine to improve coverage
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Measuring early childhood development in multiple contexts: the internal factor structure and reliability of the early Human Capability Index in seven countriesFindings support the aims of the early Human Capability Index in being adaptable and applicable for use within a range of low and middle income countries