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A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid TumorsIn this. i study the MTD and RP2D, safety, PK, and preliminary activity of single-agent ribociclib were investigated in patients with neuroblastoma.
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Late talkers and later language outcomes: Predicting the different language trajectoriesThe aim of the current study was to investigate the risk factors present at 2 years for children who showed language difficulties that persisted
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Defining the role of common variation in the genomic and biological architecture of adult human heightUsing genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability...
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Comorbidities of Attention Deficit Hyperactivity Disorder: Pregnancy Risk Factors and Parent Mental HealthOur study examined the risk of maternal smoking and alcohol consumption in pregnancy associated with child comorbidity in a community sample of children...
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The MOBI-Kids Study Protocol: Exposure to Electromagnetic Fields from Wireless Telecommunication Technologies and Possible Association with Brain Tumor RiskThe rapid increase in mobile phone use in young people has generated concern about possible health effects of exposure to radiofrequency (RF) and extremely...
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Prenatal, perinatal, and neonatal risk factors for specific language impairment: A prospective pregnancy cohort studyAlthough genetic factors are known to play a causal role in specific language impairment (SLI), environmental factors may also be important. This study...
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The effect of endotracheal tubes versus laryngeal mask airways on perioperative respiratory adverse events in infants: A randomised controlled trialEvaluating the difference of the effects of Laryngeal mask airways compared to endotracheal tubes in older children (>1 year) in incidents of PRAE in infants.
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Barriers to Parent–Child Book Reading in Early ChildhoodParent–child book reading interventions alone are unlikely to meet needs of children and families for whom the absence of reading is psychosocial risk factor
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Respiratory function and symptoms in young preterm children in the contemporary eraPreterm children have worse lung function than healthy controls
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Prevalence, clinical investigation, and management of gallbladder disease in Rett syndromeThis study determined the prevalence of cholelithiasis and/or cholecystectomy in Rett syndrome, described gallbladder function in a clinical cohort, and...
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Improving cardiovascular outcomes among Aboriginal Australians: Lessons from research for primary carePrimary care practitioners have an important role in improving Aboriginal cardiovascular care outcomes
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Western Australia unveils advances in linked data delivery systemsThis paper explains advances in extracting linked health data from the WA Data Linkage Branch
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Prior human papillomavirus-16/18 AS04-adjuvanted vaccination prevents recurrent high grade cervical intraepithelial neoplasia after definitive surgical therapyWomen who undergo surgical therapy for cervical lesions after vaccination with the HPV-16/18 vaccine may continue to benefit from vaccination
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Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997-2007: A longitudinal studyA recent longitudinal study reported an association between fine particulate (PM2.5) exposure and preterm birth (PTB) in a US cohort.
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Impairment of motor skills in children with fetal alcohol spectrum disorders in remote Australia: The Lililwan ProjectAlmost of 10% of children with FASD has significant motor impairment. Evaluation of motor function should routinely be included in assessments for FASD.
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Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesisTwo competing theories address the influence of foetal testosterone on cerebral laterality: one proposing exposure to high foetal testosterone concentrations...
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The emerging role of the urban-based aboriginal peer support worker: A Western Australian studyAboriginal Peer Support Workers identified their emerging integral role in the development of this unique culturally acceptable home visiting support for Aboriginal parents
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Nutritional Influences on Epigenetic Programming. Asthma, Allergy, and ObesityReliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also...
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The Association of Fly-in Fly-out Employment, Family Connectedness, Parental Presence and Adolescent WellbeingImportance of strengthening family connections within fly-in fly-out households. Suggestions have been made to help fly-in fly-out parents to stay in touch with their families
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Re-analysis of the association between perinatal androgens and postnatal head circumference growthThis paper is a correction of an earlier report that identified a link between exposure to high levels of testosterone during pregnancy and reduced head...