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Research

Missed Opportunities for Diagnosing Acute Rheumatic Fever

We have read with interest the new publication by Rouhiainen and colleagues on missed opportunities for preventing or diagnosing acute rheumatic fever (ARF).

Research

The Cold Atmospheric Plasma Inhibits Cancer Proliferation Through Reducing Glutathione Synthesis

Cold atmospheric plasma (CAP) is a safe and effective alternative to radiotherapy for cancer treatment. Its anticancer effects are attributed to increased intracellular reactive oxygen species (ROS). Glutathione, a key antioxidant derived from glutamine, is critical for cell proliferation. This study investigated whether CAP-induced ROS elevation results from reduced glutamine-glutathione conversion and elucidates the underlying mechanisms.

Research

Development and Validation of a Stability-Indicating RP-HPLC Method for Edaravone Quantification

Edaravone is used to treat motor neurone disease (MND) by slowing disease progression and prolonging survival time. Currently, it is available as an IV infusion (Radicava®, Jersey City, NJ, USA) and an oral liquid suspension (Radicava ORS®, Jersey City, NJ, USA). Development of novel edaravone formulations is still an active field of research that requires a validated stability-indicating assay capable of providing specific, precise, and accurate quantification of edaravone content. 

Research

Relationship between group B Streptococcal rectovaginal colonization and Vitamin D deficiency in pregnant women

Vitamin D has been recognized to have a significant impact on modulating immune response in the host body. The relationship between deficiency of Vitamin D and rectovaginal colonization with Group B Streptococcus (GBS) in pregnant women is still not well understood. 

Pooling knowledge: ORIGINS spurs global network

Researchers leading WA’s landmark ORIGINS Project have spearheaded a global network that will see them join forces with similar interventional cohort studies across the world to maximise data collection and learnings for

Vaccine push cuts meningococcal cases

Ten years of dedicated research investigating the Meningococcal ACWY vaccine paid off 20 times over in 2019, after its inclusion on the National Immunisation Program saw a significant decrease in children being diagnosed with the deadly disease.

The endgame strategy to eliminate deadly heart disease

Five years of intensive collaboration between researchers, clinicians, Aboriginal Community Controlled Health Organisations, and government and non-government organisations have finally put the long-fought for goal of ending RHD within reach.

Research

Assisted Reproductive Technologies

Assisted reproductive technologies (ART) cover a range of methods used to help couples with fertility problems achieve pregnancy, including in-vitro fertilisation (IVF).

Communications science to shift public thinking

Despite major advances in science in recent years, many Australians still don't understand the magnitude and importance of early years development to a child's life journey.

Counting the cost of late intervention

Leaders in the not-for-profit, research, philanthropy and business sectors have joined forces to shine a light on the human and economic benefits of early support for Australian children.