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Research

Cochrane corner: hearing aids for mild to moderate hearing loss in adults

The evidence supports the widespread provision of hearing aids as the first-line clinical management for those seeking help for hearing difficulties

Research

Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome

IgG3 levels and proportions of IgG3 (%IgG) in serum at CIS diagnosis were inversely correlated with the time until conversion to MS

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Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosis

Higher IDO and ARG expression in clinically isolated syndrome and multiple sclerosis provides one sustained homeostatic mechanism to control multiple sclerosis-associated inflammation

Research

Cardiometabolic risk factors at 5 years after omega-3 fatty acid supplementation in infancy

Supplementation with n-3 LCPUFA in infancy revealed a reduction in waist circumference at 5 years

Research

Comprehensive investigation of congenital anomalies in cerebral palsy: Protocol for a European-Australian population-based data linkage study

The aim of this study is to generate new knowledge about the aetiologies of CP through a focused investigation into the role of congenital anomalies

Research

Structure-function relationships of the neisserial EptA enzyme responsible for phosphoethanolamine decoration of lipid A: Rationale for drug targeting

This review concentrates on the phosphoethanolamine decoration of lipid A in the pathogenic species of the genus Neisseria

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Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma

Airway interleukin-33 is associated with type-2 cytokines in naturally occurring asthma exacerbations in adults

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Dysregulated IL-1β-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine

We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever

Research

PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

Our findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis

Research

Active surveillance of 2017 seasonal influenza vaccine safety: An observational cohort study of individuals aged 6 months and older in Australia

AusVaxSafety surveillance demonstrated comparable and expected safety outcomes for the 2017 quadrivalent inactivated influenza vaccine brands used in Australia