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CGM and exercise trialChildren with Type 1 Diabetes (aged eight to 12 years) are needed for a new trial into Continuous Glucose Monitoring (CGM) and exercise.
News & Events
Sprint studyJoin us in Western Australia's first home-based study looking at the effect of sprinting during exercise in Type 1 Diabetes.
News & Events
Transitioning from paediatric to adult diabetes servicesThe period of transition between paediatric (child) services and adult-based services is a sensitive one for patients with diabetes.
Find out what the Children's Diabetes Centre is and what research it is conducting.
Pump Comparison tool . This easy-to-use updated comparison tool is designed to help you pick the right device for your family.
Websites we think you'll find useful.
Research
The Brain Basis of Comorbidity in Neurodevelopmental DisordersThis review discusses early brain development and the etiological factors that may give rise to atypical developmental trajectories, along with neuroimaging insights
Research
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastomaMedulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.
Research
Immunogenicity and Immune Memory after a Pneumococcal Polysaccharide Vaccine Booster in a High-Risk Population Primed with Pneumococcal Conjugate VaccinePPV is immunogenic in 9-month-old children at high risk of pneumococcal infections and does not affect the capacity to produce protective immune responses
Research
Trial refresh: A case for an adaptive platform trial for pulmonary exacerbations of cystic fibrosisThis review will discuss the necessary steps required for a Bayesian adaptive platform trial to optimize treatment of pulmonary exacerbations of cystic fibrosis