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Research

Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models

This JAK3A572V knockin model is a relevant new tool for testing the efficacy of JAK inhibitors in JAK3-related hematopoietic malignancies

Research

Respiratory function in healthy Emirati children using forced oscillations

Forced oscillation technique measurements were feasible in Emirati school-children. New forced oscillation technique reference equation in Emirati children were derived.

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Using linked data to investigate developmental vulnerabilities in children of convicted parents

Although children of convicted parents experience a higher incidence of sociodemographic risk, their parents' criminal activity constitutes an independent risk factor for their development

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How New and Expecting Fathers Engage With an App-Based Online Forum: Qualitative Analysis

These data show that fathers are prepared to use a breastfeeding-focused online forum in a variety of ways to facilitate social support

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Construct validity and responsiveness of the functional Tactile Object Recognition Test for children with cerebral palsy

The functional Tactile Object Recognition Test demonstrated preliminary construct validity, and was positively associated with an upper limb activity measure

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Evaluation of a public education campaign to support parents to reduce adolescent alcohol use

The Parents, Young People and Alcohol campaign achieved high awareness and positively influenced parental outcomes

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Elucidating the genetic architecture of Adams-Oliver syndrome in a large European cohort

The purpose of this study was therefore to comprehensively examine the genetic architecture of Adams-Oliver syndrome in an extensive cohort

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Predicting disease progression in cystic fibrosis

Comprehensive scores incorporating clinical, lung function, imaging and laboratory data will become essential in the future for predicting disease progression and for use in clinical trials

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Navigating 'the system' to find supports and services for people with developmental disability: How can research help make this a better journey?

Parents navigate what can be a confusing world of early intervention services, residing in the health, disability and/or education sectors