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Mining single-cell data for cell type-disease associations

A robust understanding of the cellular mechanisms underlying diseases sets the foundation for the effective design of drugs and other interventions. The wealth of existing single-cell atlases offers the opportunity to uncover high-resolution information on expression patterns across various cell types and

Food Allergy Genetics and Epigenetics: A Review of Genome-Wide Association Studies

In this review, we provide an overview of food allergy genetics and epigenetics aimed at clinicians and researchers. This includes a brief review of the current understanding of genetic and epigenetic mechanisms, inheritance of food allergy, as well as a discussion of advantages and limitations of the different types of studies in genetic research. 

Real world effectiveness of early ensitrelvir treatment in patients with SARS-CoV-2, a retrospective case series

Ensitrelvir, a 3C-like protease inhibitor, received emergency approval in Japan in November 2022 for treating non-hospitalized patients with mild-to-moderate COVID-19. However, confirmation of its real-world clinical effectiveness is limited.

Protocol to implement and evaluate a culturally secure, strength-based, equine-assisted learning program, "Yawardani Jan-ga" (horses helping)

Australian Aboriginal people experience stressors from inequalities across crucial social determinants, including deep and entrenched disadvantage and exclusion. The impact of unaddressed historical issues is pervasive and intergenerational. The disproportionate rates of Aboriginal youth suicide, juvenile detention and imprisonment highlight the inadequacy of existing social and emotional wellbeing programs and services for Aboriginal children and young people.

Invasive Fungal Disease in Immunocompromised Children: Current and Emerging Therapies

In an era of expanding indications for iatrogenic immunosuppression, invasive fungal disease (IFD) remains a significant challenge in immunocompromised children, with case fatality rates ranging from 10 to 70%. Understanding of current recommendations and recent evidence is essential to guide optimal IFD management.

The Kids researchers honoured at Premier’s Science Awards

A The Kids Research Institute Australia researcher devoted to Aboriginal health and justice has been named the inaugural Shell Aboriginal STEM Student of the Year at the 2019 Premier’s Science Awards.

Hon. Julie Bishop to join Human Vaccines Project board

The Kids Research Institute Australia Chair Hon. Julie Bishop will join the international Human Vaccines Project’s Board of Directors on its mission to address the next frontier of human health – decoding the human immune system to transform how we prevent, diagnose and treat disease.

Funding for stillbirth autopsies will enable life-saving research

Researchers from The Kids Research Institute Australia say the Federal Government’s in-principle commitment to cover the cost of stillbirth autopsies is a positive step forward in addressing the nation’s stagnating rates.

Meet the The Kids Sarcoma Translational Research Team

This year for Childhood Cancer Awareness Month, we got to know the sarcoma research team at Telethon Kids.

Churchill Fellow to explore how other countries get kids back to school

The Kids Research Institute Australia researcher Dr Kirsten Hancock will use a prestigious Churchill Fellowship to investigate how other countries handle school absenteeism.