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To address the urgent need for a vaccine for COVID-19, BioNet’s gene-based vaccine, COVIGEN, will be investigated in this first-in-human, Phase I study.
Elke Jennifer Peter Seppanen Kent Richmond BSc PhD RN MBBS MRCP(UK) FRACP Program Manager, Bacterial Respiratory Infectious Disease Group Clinical
Children in the tiny Pacific nation of Tuvalu face a unique threat that should be a wake-up call to other countries across the world.
Dissociative disorders in children and young adolescents are under-recognised and under-treated. Current diagnostic criteria rely on downward extensions of adult models and do not adequately consider developmental differences in younger populations. This reliance risks overlooking symptom patterns that may be unique in childhood, thereby perpetuating diagnostic gaps and delayed treatment.
Post-acute sequelae of COVID-19 (PASC), or long COVID, are a public health concern. While most recover from SARS-CoV-2 infections within weeks, some experience persistent symptoms. Here, we quantified the association between repeated SARS-CoV-2 infections and the risk of hospital-diagnosed PASC.
To explore Aboriginal families' experiences of recognising clinical deterioration and raising their concerns within the Paediatric ESCALATION system to identify enablers and barriers to family involvement.
Digital interventions have emerged as promising tools to support mental well-being in diabetes. This review aimed to evaluate the effectiveness of digital health interventions in improving mental health outcomes among adults with diabetes, as well as assess the methodological quality of relevant studies and provide a commentary on research gaps and future directions.
Few studies have explored associations between indexes incorporating both breastfeeding and complementary feeding and future risk of overweight/obesity. The aim of this study was to explore associations between a previously developed Infant Diet Score (IDS; higher score reflecting better alignment with breastfeeding and complementary feeding guidelines in the first year of life), and the risk of overweight and/or obesity in childhood.
To map and systematise existing research on the use of artificial intelligence (AI) in mental health-based diabetes care contexts, identify trends and potential gaps in the literature, examine methodological limitations and highlight future research directions.
Clinical trial designs are typically narrowly focused on error control in hypothesis testing, but this approach is inadequate in many contexts, particularly when a decision maker intends to, or must, consider multiple relevant clinical and health economic outcomes under uncertainty. Value-of-information (VoI) metrics can be used to estimate the monetary value of data collection to the decision maker.