Reports and Findings
Research
Vulnerable from the first breath - epithelial dysfunction and respiratory outcomes in childrenWe have been studying the importance of the epithelial cells lining the airways in the nose and lungs.
Research
Epithelial Drivers of Neutrophil Plasticity in Early Cystic Fibrosis Lung DiseaseHallmarks of cystic fibrosis (CF) airway disease include bronchiectasis, airway inflammation by infiltrating polymorphonuclear neutrophils (PMNs) and recurring infection.
Research
Developing a novel therapeutic pipeline for antibiotic resistant bacterial lung infection in children: investigating and assessing the potential phage therapyAntimicrobial resistance is a global health crisis, which has accelerated due to the overuse of antibiotics.
Research
Defective cell migration as a mechanism of dysregulated asthmatic airway repairThe findings from this study show that in children with asthma this protective barrier is different from children without asthma.
Research
Cultures of HRV-C for investigations of pathogenesis in childrenAnthony Belinda Ingrid Kicic Hales Laing BSc (Hons) PhD BSc (Hons) PhD BSc PhD Rothwell Family Fellow; Head, Airway Epithelial Research Senior Manager, Research Platforms Head, Children's Respiratory Science 6319 1828 Anthony.Kicic@thekids.org.au
Research
Children’s regenerative and genetic medicine programThe project aims to build capacity in regenerative medicine for children with respiratory diseases.
Research
A tonsil organ model to evaluate carriage, disease mechanisms and therapeutic interventions for the treatment and prevention of Group A Streptococcus infectionsAnthony Tim Kicic Barnett BSc (Hons) PhD PhD Rothwell Family Fellow; Head, Airway Epithelial Research Head, Strep A Pathogenesis and Diagnostics Anthony.Kicic@thekids.org.au timothy.barnett@thekids.org.au Rothwell Family Fellow; Head, Airway
Research
The next generation of impact in cystic fibrosisLung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment.
Research
Preterm Paediatric Inhaled Corticosteroids Intervention (PICSI)Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm.
Research
Developing sensitive endpoints for respiratory disease progression in children with neuromuscular diseaseWe hope that through earlier diagnosis and treatment of muscle weakness during sleep, we can prevent future lung failure in children with neuromuscular disorders.