Reports and Findings (Published Research)

Research

Lower Cord Blood IL-17 and IL-25, but Not Other Epithelial Cell-Derived Cytokines Are Associated with Atopic Dermatitis in Infancy

There is a growing need for early biomarkers that may predict the development of atopic dermatitis (AD). As alterations in skin barrier may be a primary event in disease pathogenesis, epithelial cell (EC) cytokines expression patterns may be a potential biomarker in early life to target allergy preventive strategies towards "at-risk" infants. The aim of this longitudinal investigation was to examine from birth over the course of infancy levels of the EC cytokines: thymic stromal lymphopoietin (TSLP), interleukin (IL)-33, IL-25, and IL-17 in infants at high-risk of AD due to maternal atopy.

Research

Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients

Cystic fibrosis (CF) is a congenital disorder resulting in a multisystemic impairment in ion homeostasis. The subsequent alteration of electrochemical gradients severely compromises the function of the airway epithelia.

Research

Ending rheumatic heart disease in Australia: the evidence for a new approach

The RHD Endgame Strategy: the blueprint to eliminate rheumatic heart disease in Australia by 2031 (the Endgame Strategy) is the blueprint to eliminate rheumatic heart disease (RHD) in Australia by 2031. Aboriginal and Torres Strait Islander people live with one of the highest per capita burdens of RHD in the world.

Research

"Cultural Security Is an On-Going Journey..." Exploring Views from Staff Members on the Quality and Cultural Security of Services for Aboriginal Families in Western Australia

Cultural security is a key element of accessible services for Indigenous peoples globally, although few studies have examined this empirically. We explored the scope, reach, quality, and cultural security of health and social services available to Aboriginal and/or Torres Strait Islander families in Western Australia (WA), from the point of view of staff from the services.

Research

Innate Immune Responses and Gut Microbiomes Distinguish HIV-Exposed from HIV-Unexposed Children in a Population-Specific Manner

In both high- and low-income countries, HIV-negative children born to HIV-positive mothers (HIV exposed, uninfected [HEU]) are more susceptible to severe infection than HIV-unexposed, uninfected (HUU) children, with altered innate immunity hypothesized to be a cause. Both the gut microbiome and systemic innate immunity differ across biogeographically distinct settings, and the two are known to influence each other.

Research

Food Outlets Dietary Risk (FODR) assessment tool: study protocol for assessing the public health nutrition risks of community food environments

Availability and accessibility of nutritious foods can vary according to the food outlets present within a neighbourhood or community. There is increasing evidence that community food environments influence food choice.

Research

Priority-setting in youth with chronic conditions

Amy Keely Liz Leanne Elmie Bec Finlay-Jones Bebbington Davis Fried Janse Van Rensburg Sampson BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) MClinPsych/PhD MBBS FRACP PhD BSc DipEd MSpEd EdD BA, BSc BSc, BPsych (Hons) Head, Early

Research

safeTALK training for young people experiencing homelessness: a community-based trial

Penelope Yael Jacinta Strauss Perry Freeman BA, MPH, PhD BPsych (Hons) MPsych (Clin) PhD BScs, MPH Research Fellow in Youth Suicide Prevention Program Head, Mental Health & Youth; Head, Youth Mental Health Program Manager, Youth Mental Health 08

Research

Exploring LGBTQA+ young people’s experiences of suicidality: a qualitative study

Penelope Helen Yael Larissa Strauss Morgan Perry Marion BA, MPH, PhD BA (Hons), Doctor of Psychology BPsych (Hons) MPsych (Clin) PhD BPsych(Hons) Research Fellow in Youth Suicide Prevention Senior Project Coordinator Program Head, Mental Health &

Research

Uplift: Online self-compassion training for young people with chronic conditions

Amy Yael Asha Finlay-Jones Perry Parkinson BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) BPsych (Hons) MPsych (Clin) PhD BPsych (Hons) Head, Early Neurodevelopment & Mental Health; Healthway WA Senior Research Fellow Program Head,