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Humility, inquisitiveness, and openness: key attributes for meaningful engagement with Nyoongar peopleThe rebuilding of trust requires the development of meaningful relationships in order to break down the barriers so as to increase access and develop culturally secure responses by services
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Does somatosensation change with age in children and adolescents? A systematic reviewSomatosensory modalities, such as touch, proprioception and haptic ability, greatly influence the achievement of developmental milestones for children.
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Adolescent and young adult medicine in Australia and New Zealand: towards specialist accreditationThe RACP is advancing a three-tier strategy to build greater specialist capacity and sustain leadership in adolescent and young adult medicine
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What bridges the gap between self-harm and suicidality? The role of forgiveness, resilience and attachmentThere is a lack of understanding of why some people who self-harm escalate to suicidal behaviour when others do not. Psychological factors such as attachment...
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Wound healing genes and susceptibility to cutaneous leishmaniasis in BrazilHere we examined single nucleotide polymorphisms (SNPs) in these genes as risk factors for cutaneous (CL) and mucosal leishmaniasis (ML), and leishmaniasis...
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Food for thought: progress in understanding the causes and mechanisms of food allergyTreatments for food allergy are still lacking, yet progress is being made, and immunotherapy appears more effective than dietary avoidance.
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Learning to make a difference for chILD: Value creation through network collaboration and team scienceAddressing the recognized challenges and inequalities in providing high quality healthcare for rare diseases such as children's interstitial lung disease (chILD) requires collaboration across institutional, geographical, discipline, and system boundaries. The Children's Interstitial Lung Disease Respiratory Network of Australia and New Zealand (chILDRANZ) is an example of a clinical network that brings together multidisciplinary health professionals for collaboration, peer learning, and advocacy with the goal of improving the diagnosis and management of this group of rare and ultra-rare conditions.
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Structured exercise programs for higher education students experiencing mental health challenges: background, significance, and implementationThe incidence of mental illness is greatest among young adults, and those enrolled in higher education may be particularly vulnerable compared to the general young adult population. Many higher education institutions employ student support staff tasked with implementing strategies to improve student wellbeing and mental illness.
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Support needs and experiences of young people living in families with mental illnessChildren and adolescents living in families affected by mental illness are at elevated risk of developing mental health problems. A range of interventions have been designed to help these young people; however, the effectiveness of these programs is, in some cases, mixed. Our aim was to understand in detail the support needs and experiences of a group of Australian children and adolescents living in families with mental illness.
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Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in supratentorial ependymomaSupratentorial RELA fusion (ST-RELA) ependymomas (EPNs) are resistant tumors without an approved chemotherapeutic treatment. Unfortunately, the molecular mechanisms that lead to chemoresistance traits of ST-RELA remain elusive. The aim of this study was to assess RELA fusion-dependent signaling modules, specifically the role of the Hedgehog (Hh) pathway as a novel targetable vulnerability in ST-RELA.