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Research

Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours

The class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway.

Research

Big data in global health: Improving health in low- and middle-income countries

Over the last decade, a massive increase in data collection and analysis has occurred in many fields.

Research

Protecting and Promoting Young People’s Social and Emotional Health in Online and Offline Contexts

Young people's use of mobile phones and access to the Internet have increased dramatically in the last decade, especially among those aged 9-15 years.

Research

Participation in paediatric cancer studies: Timing and approach to recruitment

In this sub-study, we aimed to investigate factors that may have influenced study participation and completeness of survey completion.

Research

Prevention of neural tube defects with folate

A programme of monitoring mandatory fortification has been established in Australia.

Research

How the first nine months shape the rest of our lives

The field of the developmental origins of health and disease (DOHaD) focuses on prenatal influences as a crucial point in development.

Research

A randomized, controlled, phase 1/2 trial of a neisseria meningitidis serogroup B bivalent rLP2086 vaccine in healthy children and adolescents

Factor H binding protein (also known as LP2086) is a conserved outer membrane neisserial lipoprotein that has emerged as a strong candidate protein antigen...

Research

A geometric morphometric assessment of hand shape and comparison to the 2D: 4D digit ratio as a marker of sexual dimorphism

In this study of hand shape analysis, we introduce the reader already familiar with the field of twin research to the potential utility of geometric...

Research

An eleven-year evaluation of the effect of community treatment orders on changes in mental health service use

Many studies of compulsory community treatment have assessed their effect early on after the implementation of legislation.