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News & Events

Early Years Initiative an unprecedented commitment to youngest West Australians

Minderoo Foundation and The Kids Research Institute Australia are proud to partner with the Western Australian Government on an unprecedented $49.3 million commitment to

News & Events

Study unlocks new knowledge about the role of immune cells in asthma flare-ups

Flare-ups of asthma are usually brought on by respiratory infections, such as the common cold, and are one of the most common reasons for a child to miss school or require emergency care.

News & Events

The Kids welcomes Minderoo investment in early child development

The Kids has congratulated Andrew & Nicola Forrest on their visionary commitment to develop a new blueprint for optimal child development in Aust & beyond.

A life of caring and a passion to give - local legend Harvey Coates

Over 20 years Professor Harvey Oates has made financial contributions to The Kids totaling over 6 figures, as well as sitting on the board for 16 years.

Funding all adds up

Little or large, every donation made to The Kids Research Institute Australia is precious.

Involvement opportunities

Discover the latest community involvement opportunities from across the Institute.

National Vaccines Platform – Culturally & Linguistically Diverse Community Advisory group

Telethon Kids Institute is leading the development of a National Vaccine Platform for conducting trials to improve protection from diseases that can prevented with vaccines. We are seeking people from Culturally and Linguistically Diverse backgrounds to join our new Vaccines Community Advisory Group.

Bright Tomorrows – Community Advisory Group

We are seeking expressions of interest from community members with children between the ages of 0-5 years old to join our Community Advisory Group.

Research

The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program

Transcriptional cofactors of the ETO family are recurrent fusion partners in acute leukemia. We characterized the ETO2 regulome by integrating transcriptomic and chromatin binding analyses in human erythroleukemia xenografts and controlled ETO2 depletion models. We demonstrate that beyond its well-established repressive activity, ETO2 directly activates transcription of MYB, among other genes.

Research

A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors

Pediatric patients with recurrent and refractory cancers are in most need for new treatments. This study developed patient-derived-xenograft (PDX) models within the European MAPPYACTS cancer precision medicine trial.