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Research
Indirect effects of the COVID-19 pandemic on malaria intervention coverage, morbidity, and mortality in Africa: a geospatial modelling analysisSubstantial progress has been made in reducing the burden of malaria in Africa since 2000, but those gains could be jeopardised if the COVID-19 pandemic affects the availability of key malaria control interventions. The aim of this study was to evaluate plausible effects on malaria incidence and mortality under different levels of disruption to malaria control.
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Endemic country capacity building and decentralizationAdam Punam Susan Tolu Saddler Amratia Rumisha Okitika PhD PhD PhD (Biostatistics) BSc, MPH, PMP Research Officer Honorary Research Associate
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Geospatial modelling for malaria risk stratification and intervention targeting for high burden high impact countriesEwan Punam Susan Tasmin Cameron Amratia Rumisha Symons BSc PhD PhD PhD (Biostatistics) Director of Malaria Risk Stratification Honorary Research
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Tracking global intervention coverageAdam Dan Saddler Weiss PhD PhD Research Officer Honorary Research Fellow Daniel.Weiss@thekids.org.au Research Officer Honorary Research Fellow Adam
Focus Area
Brain and BehaviourThe Brain and Behaviour research theme consists of five programs: Child Health Analytics, Development and Disability, Healthy Behaviours and Environments, Mental Health and Youth, Population Health.
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Statistical modelling under differential privacy constraints: a case study in fine-scale geographical analysis with Australian Bureau of Statistics TableBuilder dataConsistent with the principles of differential privacy protection, the Australian Bureau of Statistics artificially perturbs all count data from the Australian Census prior to its release to researchers through the TableBuilder platform. This perturbation involves the addition of random noise to every non-zero cell count followed by the suppression of small values to zero.
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Spatio-temporal spread of artemisinin resistance in Southeast AsiaCurrent malaria elimination targets must withstand a colossal challenge-resistance to the current gold standard antimalarial drug, namely artemisinin derivatives. If artemisinin resistance significantly expands to Africa or India, cases and malaria-related deaths are set to increase substantially.
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Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in AfricaChildren recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge from hospital. However, a recent trial found that post-discharge malaria chemoprevention (PDMC) with dihydroartemisinin-piperaquine reduces this risk. We developed a mathematical model describing the daily incidence of uncomplicated and severe malaria requiring readmission among 0-5-year old children after hospitalised SMA.
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What Heterogeneities in Individual-level Mobility Are Lost During Aggregation? Leveraging GPS Logger Data to Understand Fine-scale and Aggregated Patterns of MobilityHuman movement drives spatial transmission patterns of infectious diseases. Population-level mobility patterns are often quantified using aggregated data sets, such as census migration surveys or mobile phone data. These data are often unable to quantify individual-level travel patterns and lack the information needed to discern how mobility varies by demographic groups. Individual-level datasets can capture additional, more precise, aspects of mobility that may impact disease risk or transmission patterns and determine how mobility differs across cohorts; however, these data are rare, particularly in locations such as sub-Saharan Africa.
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Antimicrobial susceptibility testing profiles of ESBL-producing Enterobacterales isolated from hospital and community adult patients in Blantyre, MalawiThere is a paucity of data on antimicrobial resistance (AMR) in Malawi. Here we present a study of AMR of extended-spectrum β-lactamases-producing Enterobacterales (ESBL-E) isolated from hospital and community settings in Blantyre, Malawi.