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Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome

IgG3 levels and proportions of IgG3 (%IgG) in serum at CIS diagnosis were inversely correlated with the time until conversion to MS

Study protocol for a self-controlled cluster randomised trial of the Alert Program to improve self-regulation and executive function in Australian Aboriginal children

This trial is evaluating the effectiveness of an Alert Program school curriculum for improving self-regulation and executive function in children living in remote Australian Aboriginal communities

Rheumatic Heart Disease Worldwide: JACC Scientific Expert Panel

The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care

How New and Expecting Fathers Engage With an App-Based Online Forum: Qualitative Analysis

These data show that fathers are prepared to use a breastfeeding-focused online forum in a variety of ways to facilitate social support

The influence of incomplete case ascertainment on measures of vaccine efficacy

A biologically active vaccine may produce a low measured vaccine efficacy under a range of epidemiological, vaccine-related and logistical conditions

Vitamin D is crucial for maternal care and offspring social behaviour in rats

These data highlight that early life levels of vitamin D are an important consideration for maternal behavioural adaptations as well as offspring neuropsychiatry

Large-Scale Structural Variation Detection in Subterranean Clover Subtypes Using Optical Mapping

The accuracy of structural variations detection by Bionano optical mapping is highly dependent on the quality of reference genomes and the density of selected nickases

Predicting language difficulties in middle childhood from early developmental milestones: A comparison of traditional regression and machine learning techniques

The current study provides preliminary evidence that machine learning algorithms provide equivalent predictive accuracy to traditional methods for language difficulties in middle childhood

Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma

This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with and without asthma

The Ultra-High-Risk for psychosis groups: Evidence to maintain the status quo

Our findings demonstrate that Ultra-High-Risk groups evidence a similar clinical risk profile when we expand this beyond transition to psychosis