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Research
Hearing aid review appointment: clients’ reasons for attendance and non-attendanceAppointment attendance is influenced by some factors modifiable by the clinician, including providing better education
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The effect of upgrades to childcare outdoor spaces on preschoolers’ physical activity: Findings from a natural experimentThis natural experiment investigated the influence of early childhood education and care outdoor physical environment upgrade on preschoolers' physical activity
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Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipientsOur data illustrate that rhinovirus infection is capable of infecting upper and lower airway epithelial cells, driving cell death and inflammation
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Genetic determinants of paediatric food allergy: A systematic reviewWe systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation
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Confounding effects of gavage in mice: Impaired respiratory structure and functionIt is therefore clear that gavage can have significant impacts on experimental animals in terms of their stress response and overall morbidity and mortality
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Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host InteractomesGenome sequencing and phylogenetic analysis of a quorum sensing positive Psychrobacter isolate identified several quorum sensing associated systems
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An assessment of computer-generated stimuli for use in studies of body size estimation and biasOur results show that perception of body size for computer-generated stimuli was non-linear
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Editorial: Insights Into Biomarkers, Cytokines, and Chemokines in Skin CancerOur current Research Topic highlights the complexity of the relationship between the skin, immune system and skin cancer
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Investing in school readiness: A comparison of different early childhood education pathways in rural IndonesiaThis paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways
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Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cellsBoth tumour suppressive and oncogenic functions have been reported for dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Herein, we performed a detailed investigation to delineate the role of DYRK1A in glioblastoma. Our phosphoproteomic and mechanistic studies show that DYRK1A induces degradation of cyclin B by phosphorylating CDC23, which is necessary for the function of the anaphase-promoting complex, a ubiquitin ligase that degrades mitotic proteins.