Search
Research
The hygiene hypothesis revisited: role of materno-fetal interactionsFor 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal innate immu
Research
Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of lifeAppropriate innate immune function is essential to limit pathogenesis and severity of severe lower respiratory infections (sLRI) during infancy, a leading cause of hospitalization and risk factor for subsequent asthma in this age group.
Research
Identification and Isolation of Rodent Respiratory Tract Dendritic CellsThis chapter describes the preparation of respiratory tract tissue from both mice and rats for the isolation of respiratory tract dendritic cells (RTDC).
Research
Comparison of neonatal T regulatory cell function in Papua New Guinean and Australian newbornsWe compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New Guinea)...
Research
Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in childrenInterleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
Research
Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort studyAtopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.
Research
Fish oil supplementation in early infancy modulates developing infant immune responsesMaternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and...
Research
Viral infections and atopy in asthma pathogenesis: New rationales for asthma prevention and treatmentProspective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a...
Research
Do early-life viral infections cause asthma?Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known
Research
Increased allergic immune response to Sarcoptes scabiei antigens in crusted versus ordinary scabiesScabies, a parasitic skin infestation by the burrowing "itch" mite Sarcoptes scabiei, causes significant health problems for children and adults worldwide.