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Research

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

Here we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia

Research

A Comparison of the Motor Skills of Young People in a Youth Detention Centre with Diagnosed Fetal Alcohol Spectrum Disorder and Prenatal Alcohol Exposure

Visual motor integration and handwriting skills were often impaired in this population of young people in a youth detention centre

Research

Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

In this Review, we consolidate the latest updates in the development of primary epithelial cellular model systems relevant for cystic fibrosis

Research

A realist evaluation of peer mentoring support for university students with autism

Standard peer mentoring approaches can be enhanced to meet the needs of students with ASD by including training for mentors on ASD

Research

Mental-health disparities between heterosexual and sexual-minority adolescents: Examining the role of informant discrepancies

Understanding informant discrepancies and their meaning is pivotal to designing surveys that generate robust insights into the health of sexual-minority adolescents

Research

Prednisolone Versus Dexamethasone for Croup: a Randomized Controlled Trial

The type of oral steroid seems to have no clinically significant impact on efficacy, both acutely and during the week after treatment

Research

The role and therapeutic implications of T cells in cancer of the lung

This review examines the role of T cells in lung cancer, discussing the direction and clinical significance of current and future immunotherapeutic strategies

Research

S. aureus colonization in healthy Australian adults receiving an investigational S. aureus 3-antigen vaccine

Based on descriptive analyses of this small study, S. aureus 3-antigen vaccine vaccination did not impact S. aureus acquisition or carriage

Research

Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactions

Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system