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Research

High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

High dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis

Research

Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight mice

Exposure to sunlight may limit cardiometabolic risk.

Research

Sun exposure and its effects on human health: Mechanisms through which sun exposure could reduce the risk of developing obesity and cardiometabolic dysfunction

The cardiometabolic protective effects of ultraviolet radiation and mechanistic pathways through which ultraviolet radiation could be beneficial.

Research

Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific manner

Maintaining sufficient vitamin D is necessary for optimal lung health, and vitamin D may modulate the lung microbiome in a sex-specific fashion

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Dietary Vitamin D Increases Percentages and Function of Regulatory T Cells in the Skin-Draining Lymph Nodes and Suppresses Dermal Inflammation

Dietary vitamin D3 increased the suppressive activity of regulatory T cells in the skin-draining lymph nodes, which are poised to suppress dermal inflammation

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Identification of genes differentially regulated by vitamin D deficiency that alter lung pathophysiology and inflammation in allergic airways disease

Vitamin D deficiency exacerbates house dust mite-induced inflammation and alterations in lung structure and function

Research

Can skin exposure to sunlight prevent liver inflammation?

Here we discuss how skin exposure to sunlight may suppress liver inflammation and the severity of NAFLD.

Research

The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung function

In this study, we aimed to uncover the molecular mechanisms contributing to altered lung structure and function.

Research

Reduced immune responses in chimeric mice engrafted with bone marrow cells from mice with airways inflammation.

During respiratory inflammation, it is generally assumed that dendritic cells differentiating from the bone marrow are immunogenic rather than immunoregulatory.

Research

Vitamin D and immunity

The active form of vitamin D has an important role in calcium metabolism and in bone mineralisation, but the evidence for other health outcomes is mixed,...