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T-cell activation genes differentially expressed at birth in CD4+ T-cells from children who develop IgE food allergyTo show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy.
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The relationship between maternal folate status in pregnancy, cord blood folate levels, and allergic outcomes in early childhoodThis study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes.
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The effects of maternal smoking on early mucosal immunity and sensitization at 12 months of ageIn this study, we examined the effects of maternal smoking as a major adverse exposure in early life, on mucosal immune function and allergen sensitization...
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BENEFIT - Breastfeeding and Eating Nuts and Eggs For Infant Tolerance TrialDebbie Susan Palmer Prescott D SL BSc BND PhD MBBS BMedSci PhD FRACP Head, Early Life & Life-Course Health Program; Team Lead, Nutrition in Early
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Screen ORIGINSDesiree Silva DS MBBS, FRACP, MPH, PhD Co-Head, The ORIGINS Project Co-Head, The ORIGINS Project Professor Desiree Silva is co-director for the
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The Engage Study: discovering and delighting in your baby - a pilot studyAndrew Desiree Gail Kandice Videos Whitehouse Watch and listen to Andrew Silva Alvares Varcin AJ DS GA KJ PhD MBBS, FRACP, MPH, PhD PhD M.Psych (
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The impact of a Mediterranean diet and physical activity in pregnancy on gestational weight gain and neonatal body composition at birth and 1 year of ageDesiree Silva DS MBBS, FRACP, MPH, PhD Co-Head, The ORIGINS Project Co-Head, The ORIGINS Project Professor Desiree Silva is co-director for the
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Mums Minds MatterAmy Jenny Susan Desiree Keerthi Finlay-Jones Downs Prescott Silva Kottampally AFJ JA SL DS KK BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin
The ORIGINS Team is studying early environments and parental physical health and genetics to uncover when and why non-communicable diseases (NCDs) develop.
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Egg-sensitised infants have elevated CD4+ effector memory T regulatory cells from birthIgE-mediated sensitisation to egg is common in infants. In some cases, the processes leading to egg sensitisation are established in early life, even before introduction to solid foods. The underlying mechanisms remain poorly understood.