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Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferaseNeisseria gonorrhoeae is an exclusively human pathogen that commonly infects the urogenital tract resulting in gonorrhoea. Empirical treatment of gonorrhoea with antibiotics has led to multidrug resistance and the need for new therapeutics. Inactivation of lipooligosaccharide phosphoethanolamine transferase A (EptA), which attaches phosphoethanolamine to lipid A, results in attenuation of the pathogen in infection models.
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Roadmap to incorporating group A Streptococcus molecular point-of-care testing for remote Australia: a key activity to eliminate rheumatic heart diseaseJonathan Asha Dylan Rosemary Janessa Jeffrey Carapetis AM Bowen Barth Wyber Pickering Cannon AM MBBS FRACP FAFPHM PhD FAHMS BA MBBS DCH FRACP PhD
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Trends in the diagnosis of Rett syndrome in AustraliaModifications to diagnostic criteria and introduction of genetic testing have likely affected the pattern and timing of Rett syndrome diagnosis...
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The all-age spirometry reference ranges reflect contemporary Australasian spirometryAdvances in statistical modelling have allowed the creation of smoothly changing spirometry reference ranges that apply across a wide age range and better...
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Reactogenicity of two 2010 trivalent inactivated influenza vaccine formulations in adultsThe objective of this tudy was to assess the reactogenicity of two 2010 trivalent inactivated influenza vaccine (TIV) formulations among adults, including...
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CD4 allergen tetramersThe introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...
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Increasing the low-glucose alarm of a continuous glucose monitoring system prevents exercise-induced hypoglycemiaThe use of continuous glucose monitoring systems (CGMSs) with low-glucose alarms is advocated as a means to decrease the risk of hypoglycemia in type-1 Diabetes
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Polymorphisms associated with normal memory variation also affect memory impairment in schizophreniaNeurocognitive dysfunction is a core feature of schizophrenia with particularly prominent deficits in verbal episodic memory.
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Collaborating with consumer and community representatives in health and medical research in Australia:The objective of this tudy was to collaborate with consumer and community representatives in the Alcohol and Pregnancy Project from 2006-2008
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Non-specific psychological distress, smoking status and smoking cessation: United States National Health Interview Survey 2005It is well established that smoking rates in people with common mental disorders such as anxiety or depressive disorders are much higher than in people...