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Research

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia

Biological changes associated with T-ALL relapse and resistance are stochastic and highly individual

Research

Hospital admission for infection during early childhood influences developmental vulnerabilities at age 5 years

This study demonstrates a pervasive effect of early life infections that require hospital admission on multiple aspects of early child development

Research

Does somatosensation change with age in children and adolescents? A systematic review

Somatosensory modalities, such as touch, proprioception and haptic ability, greatly influence the achievement of developmental milestones for children.

Research

Adolescent and young adult medicine in Australia and New Zealand: towards specialist accreditation

The RACP is advancing a three-tier strategy to build greater specialist capacity and sustain leadership in adolescent and young adult medicine

Research

What bridges the gap between self-harm and suicidality? The role of forgiveness, resilience and attachment

There is a lack of understanding of why some people who self-harm escalate to suicidal behaviour when others do not. Psychological factors such as attachment...

Research

Helicobacter pylori overcomes natural immunity in repeated infections

Helicobacter pylori infection does not promote an immune response protective against future reinfection

Research

CDKL5 variants: Improving our understanding of a rare neurologic disorder

Providing new insights into the interpretation of genetic variants in a rare neurologi disorder, in the contexts of population sequencing data.

Research

Incidence of and risk factors for hospitalisations due to vascular complications: A population-based type 1 diabetes cohort (n=1316) followed into early adulthood

Determining the incidence of hospitalisations and risk factors for vascular complications experienced during early adulthood in patients with childhood T1D

Research

Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?

We conducted an investigation of all cases coded as anaphylaxis presenting to the main tertiary PED in Perth, Australia, where all coding is performed by staff.

Research

Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI

This study aimed to identify a CIS peripheral blood signature that may provide clues for potential immunomodulatory approaches early in disease