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Infant MLL-AF4-driven acute lymphoblastic leukemia (ALL) is a devastating disease with dismal prognosis. A lack of understanding of the unique biology of this disease, particularly its prenatal origin, has hindered improvement of survival. We perform multiple RNA sequencing experiments on fetal, neonatal, and adult hematopoietic stem and progenitor cells from human and mouse.
We found that BCG, in a mouse model of neonatal polymicrobial sepsis, induced granulocyte colony-stimulating factor (G-CSF) within hours of administration
This paper reports on a five-year project to measure student wellbeing across an education system using the Middle Years Development Instrument
Longer suspends and fewer glycemic excursions occur at night compared with day
Language diversity and the prevalence of language disorder associated with FASD among a representative sample of youth sentenced to detention in WA
Promotion of regular physical activity is an integral part of diabetes care delivery and health care providers should promote this message at every available opportunity
The evidence supports the widespread provision of hearing aids as the first-line clinical management for those seeking help for hearing difficulties
Although children of convicted parents experience a higher incidence of sociodemographic risk, their parents' criminal activity constitutes an independent risk factor for their development
This chapter focuses on the management of those with hearing impairment, and how tele-audiological tools and approaches may assist to improve service delivery
This study sought to determine relationships, by gender, between childhood behaviour problems and adolescent risky sexual behaviours and substance use.