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Research
Pertussis burden and acellular pertussis vaccine effectiveness in high risk childrenPertussis hospitalisation is more common among infants born prematurely, who have significant comorbidities, or are Indigenous, but acellular pertussis (aP) vaccine effectiveness (VE) estimates in these sub-groups are lacking. We measured aP VE by Indigenous status, and policy-relevant categories of prematurity and comorbidity, in a population-based Australian cohort.
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Procedural anesthesia and sedation for children undergoing diagnostic and medical procedures — A review of postprocedural pain, nausea, and vomiting by questionnaire-based surveySedation and anesthesia are widely used to relieve pain and ensure cooperation during elective diagnostic and medical procedures in the pediatric population. However, there is currently limited evidence about the recovery trajectory following deep sedation or general anesthesia for such procedures in children.
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Comparison of two measures of behavior change in children after day surgeryA contemporary, well-validated instrument for the measurement of behavior change in children after general anesthesia is lacking. The Post Hospitalization Behavior Questionnaire for Ambulatory Surgery (PHBQ-AS) has been developed as an updated version of the original Post Hospitalization Behavior Questionnaire (PHBQ) to better reflect the current patient population and modern anesthetic practices.
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An eight-plex immunoassay for Group A streptococcus serology and vaccine developmentGroup A Streptococcus (GAS) is a major human pathogen responsible for superficial infections through to life-threatening invasive disease and the autoimmune sequelae acute rheumatic fever (ARF). Despite a significant global economic and health burden, there is no licensed vaccine available to prevent GAS disease. Several pre-clinical vaccines that target conserved GAS antigens are in development.
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Epigenetics in infectious diseasesViruses, bacteria, and parasites have developed strategies to invade and establish long-term infections in their hosts.
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Reduced forced vital capacity in Aboriginal Australians: Biology or missing evidence?This editorial article addresses chronic obstructive pulmonary disease and lung function testing in Aboriginal Australians.
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The stark reality of rheumatic heart diseaseThis editorial refers to ‘Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart...
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Respiratory impedance in healthy unsedated South African infants: Effects of maternal smokingNon-invasive techniques for measuring lung mechanics in infants are needed for a better understanding of lung growth and function...
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Surveillance of antenatal influenza vaccination: Validity of current systems and recommendations for improvementAlthough influenza vaccination is recommended during pregnancy as standard of care, limited surveillance data are available for monitoring uptake.
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What we know about suicide prevention for Aboriginal and Torres Strait Islander peoplesThis fact sheet addresses what we currently know about suicide prevention for Aboriginal and Torres Strait Islander peoples.