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Initial findings suggest the potential of the instrument in helping identifying positive veteran teachers within systems, as well as the voracity of the research approach

Research

These data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course

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This Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children

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GWAS results provide firm confirmation for the importance of antigen presentation and the regulation of IFNγ in determining the outcome of Leishmania infections

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Immunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. However, the majority of treated patients do not respond. Understanding immune mechanisms that underlie responsiveness to ICT will help identify predictive biomarkers of response and develop treatments to convert non-responding patients to responding ones. ICT primarily acts at the level of adaptive immunity. The specificity of adaptive immune cells, such as T and B cells, is determined by antigen-specific receptors.

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Invasive group A streptococcal infection in Australian children is frequently severe and has a high long-term morbidity burden

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There is an urgent need to develop high-quality falls prevention services for older adults with intellectual disability

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Systematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase

Research

The study highlights the need for support for parents and carers of young people who engage in self-harm

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The current effectiveness trial evaluated the combination of a whole-school program designed to prevent bullying perpetration and victimization