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Early intensification with postinduction myeloid-type chemotherapy courses did not significantly improve outcome for infant acute lymphoblastic leukemia

In this study, we investigate the in vivo synergy between romidepsin and cytarabine

We found two known risk factors in a large cohort of children treated for ALL and identified other factors associated with venous thromboembolism

Our data emphasize the heterogeneity of NMC and highlights genetic aberrations that could be explored to improve therapeutic strategies.

Mental health benefits of a pedometer-based exercise intervention for parents of children with cancer were identified.

All children who are receiving therapy for cancer should receive a single dose of PCV13 as soon as possible after diagnosis, regardless of prior PCV exposure.

We identified consistent hypomethylation of the CTGF locus in primary pre-B ALL specimens regardless of CTGF expression.

To identify links between drug resistance and gene deregulation we used oligonucleotide microarray technology.

We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis.

Investigation of this rare mixed lineage leukemia cytogenetic abnormality aims to provide further evidence of the genetic changes that underpin this leukemia.