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Research

Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in Children

Human Respiratory Syncytial Virus and Human Rhinovirus are the most frequent cause of respiratory tract infections in infants and children and are major triggers of acute viral bronchiolitis, wheezing and asthma exacerbations.

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The development of a consensus statement for the prescription of powered wheelchair standing devices in Duchenne muscular dystrophy

PURPOSE: To develop a consensus statement for the prescription of a Powered Wheelchair Standing Device (PWSD) in young people with Duchenne muscular dystrophy (DMD). MATERIALS AND METHODS: An international multidisciplinary panel comprising clinicians and users (young people with DMD) along with their parents was consulted. A literature review was undertaken and a Delphi method was utilised to generate consensus statements.

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Long-term economic outcomes for interventions in early childhood: protocol for a systematic review

Investment in early childhood produces positive returns: for the child, the family and the community.

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Investing in school readiness: A comparison of different early childhood education pathways in rural Indonesia

This paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways

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A population health approach in education to support children's early development: A Critical Interpretive Synthesis

The results from this review indicate that it would indeed be plausible to adapt the population health approach to sites and schools

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Patterns of multiple risk exposures for low receptive vocabulary growth 4-8 years in the Longitudinal Study of Australian Children

Our results demonstrate a range of multiple risk profiles in a population-representative sample of Australian children and highlight the mix of risk factors faced by children

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Birth outcomes and academic achievement in childhood: A population record linkage study

This study used population-based record linkage to examine the association between early life risk factors and academic achievement.

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Breastfeeding and early child development: A prospective cohort study

Breastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find...

Research

Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.

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Skin-Microbiome Assembly in Preterm Infants during the First Three Weeks of Life and Impact of Topical Coconut Oil Application

The structure and function of infant skin is not fully developed until 34 weeks of gestation, and this immaturity is associated with risk of late-onset sepsis (LOS). Topical coconut oil improves preterm-infant skin integrity and may reduce LOS. However, data on early-life skin-microbiome succession and potential effects of emollient skin care in preterm infants are scarce.