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Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease. What did you find? We focused on lipid molecules which we know
The effect of 100% oxygen on tidal breathing parameters in preschool children Does 100% oxygen change the way children breathe? The multiple breath
Research
Lung inflammation and simulated airway resistance in infants with cystic fibrosisCystic fibrosis (CF) is characterized by small airway disease; but central airways may also be affected. We hypothesized that airway resistance estimated from computational fluid dynamic (CFD) methodology in infants with CF was higher than controls and that early airway inflammation in infants with CF is associated with airway resistance.
Research
Systems biology and bile acid signalling in microbiome-host interactions in the cystic fibrosis lungThe study of the respiratory microbiota has revealed that the lungs of healthy and diseased individuals harbour distinct microbial communities. Imbalances in these communities can contribute to the pathogenesis of lung disease. How these imbalances occur and establish is largely unknown. This review is focused on the genetically inherited condition of Cystic Fibrosis.
Research
BAL Inflammatory Markers Can Predict Pulmonary Exacerbations in Children With Cystic FibrosisPulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing long-term morbidity. Research question: Is it possible to predict pulmonary exacerbations in children with cystic fibrosis, using inflammatory markers obtained from BAL fluid?
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$3.4mill to improve treatment management of cystic fibrosisThe Kids researchers have been awarded over $3.4 million for a new trial to pioneer improved ways for managing cystic fibrosis (‘CF’).
Promoting healthier lives for children with Cystic Fibrosis
A clinical trial is a scientific study, or an organised test of medicines and new treatment options, involving patient and non-patient human volunteers.
Lung inflammation and simulated airway resistance in infants with cystic fibrosis Cystic fibrosis (CF) is characterized by small airway disease; but
Phagocyte extracellular traps in children with neutrophilic airway inflammation Childhood lung infection is often associated with prominent