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Research

Broad perspectives of allergen specific immunotherapy

Allergen specific immunotherapy aims to subvert or divert immune responses to allergens to ones that do not cause immunological hypersensitivities.

Research

Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception.

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Adversity and resilience amongst resettling Western Australian paediatric refugees

Refugee children have complex backgrounds with exposure to multiple traumatic events.

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Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens

The poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput.

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Dedicated paediatric Outpatient Parenteral Antimicrobial Therapy medical support: a pre-post observational study

We examined the impact of introducing a dedicated team to OPAT, to define the role of increased medical oversight in improving patient outcomes in this cohort.

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Relationship between early motor milestones and severity of restricted and repetitive behaviors in children and adolescents with autism spectrum disorder

This study provides the first evidence for the association between restricted and repetitive behaviors and age of attainment of early motor milestones.

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Randomized controlled trial of early regular egg intake to prevent egg allergy

We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema.

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Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza

These findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease.

Research

Latent Class Analysis of Neurodevelopmental Deficit After Exposure to Anesthesia in Early Childhood

Some studies suggest an association between early exposure to anesthesia, surgery and long term developmental deficit, clinical phenotype of children is unknown