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Research
Geographical disparities in emergency department presentations for acute respiratory infections and risk factors for presentingOne in four ED presentations in WA children are for ARIs, representing a significant out-of-hospital burden with some evidence of geographical disparity
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Cerebral palsy trends in Australia (1995-2009): a population-based observational studyBirth prevalence of CP declined. Encouragingly, the percentage of children with CP whose disability was moderate to severe also decreased
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Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA StudyFindings provide novel insight into the composition of the gut virome during pregnancy and demonstrate a distinct profile of viruses in women with type 1 diabetes
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The Global Lung Function Initiative (GLI) Network ERS Clinical Research Collaboration: how international collaboration can shape clinical practiceThe Global Lung Function Initiative is working to improve the interpretation of lung function: an update on current work and the opportunities for further engagement
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Friendly Schools Universal Bullying Prevention Intervention: Effectiveness with Secondary School StudentsThis study demonstrates the importance of considering the effectiveness of secondary school bullying prevention interventions and real-world implementation support
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The fall and rise of Group A Streptococcus diseasesWe overview the changing epidemiology of Group A Streptococcus infections and the genetic alterations that accompany the emergence of Group A Streptococcus strains
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Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade gliomaBevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity
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Prevalence of electronic device use before bed among Australian children and adolescents: a cross-sectional population level studyTo understand the prevalence of children and adolescents’ electronic device use (EDU) in the hour before bed and identify sociodemographic groups that are at increased risk of problematic use.
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Sex-Specific Environmental Impacts on Initiation and Progression of Multiple SclerosisThe immunological mechanisms that contribute to multiple sclerosis (MS) differ between males and females. Females are 2-3 times more likely to develop MS compared to males, however the reason for this discrepancy is unknown. Once MS is established, there is a more inflammatory yet milder form of disease in females whereas males generally suffer from more severe disease and faster progression, neural degradation, and disability.
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Clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation (CASSETTE)-an open-labelled pilot randomized controlled trialCombination antibiotic therapy with an antitoxin agent, such as clindamycin, is included in some guidelines for severe, toxin-mediated Staphylococcus aureus infections. The evidence to support this practice is currently limited to in vitro, animal and observational human case-series data, with no previous randomized controlled trials (RCTs).