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Research

Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted Therapeutics

We investigated the relationship between the sensitivity of hundreds of cell lines to hundreds of drugs, and the relative expression levels of the targets

Research

Exploring stakeholders' perceptions of the acceptability, usability, and dissemination of the australian 24-hour movement guidelines for the early years

This study examined stakeholders' perceptions regarding the acceptability, usability, and dissemination of the Australian 24-Hour Movement Guidelines

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Systems biology and big data in asthma and allergy: recent discoveries and emerging challenges

We describe recent "omic"-level findings, and examine how these findings have been systematically integrated to generate further insight

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Effects of UVR exposure on the gut microbiota of mice and humans

Both human and murine studies report that multiple exposures to sub-erythemal UV radiation can increase the diversity of the gut microbiome

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Sun exposure: An environmental preventer of metabolic dysfunction?

Emerging preclinical findings suggest that some sun exposure is necessary for optimal metabolic health

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Intrauterine growth restriction affects diaphragm function in adult female and male mice

Sex and intrauterine growth restriction independently affect diaphragm contraction in adult mice without changes in structure

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Sharing is Caring: A Study of Food-Sharing Practices in Australian Early Childhood Education and Care Services

This paper supports the practice of food sharing in Early Childhood Education and Care settings and calls for them to become embedded in everyday operations

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Maternal Alcohol-Use Disorder and Child Outcomes

The effects of maternal alcohol-use disorder are experienced by the majority of exposed children rather than a vulnerable subgroup of this population

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Associations between School Readiness and Student Wellbeing: A Six-Year Follow Up Study

It is well established that children’s school readiness is associated with their later academic achievement, but less is known about whether school readiness is also associated with other measures of school success, such as students’ social and emotional wellbeing. While some previous research has shown a link between early social and emotional development and student wellbeing, results are mixed and the strength of these relationships vary depending on whether data is based on child, teachers or parents ratings and which specific student wellbeing outcomes are measured.

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Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy in inducing desensitisation or tolerance in children with peanut allergy compared with oral immunotherapy

Peanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities.