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Research
Group A streptococcal vaccines: Paving a path for accelerated developmentVaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades.
Research
Progress toward a global Group A streptococcal vaccineThe desire for an effective vaccine arises from the large burden of disease caused by the bacterium, particularly rheumatic fever and rheumatic heart disease.
News & Events
Vaccination Q&A with Dr Chris BlythImmunisation plays an important role in preventing disease within our community. Watch Dr Chris Blyth answer some commonly asked questions about vaccines.
News & Events
An open letter to WA familiesMy colleagues and I at Perth's The Kids Research Institute Australia study how to make current vaccines work better, reduce common side effects, and develop new vaccines.
News & Events
New vaccine may provide broader protection against cervical cancerJust under 150 Perth women have contributed to major international research at the Telethon Institute for Child Health Research.
News & Events
Perth researchers to trial bird flu vaccinePerth researchers have begun a trial to test the effectiveness of a new vaccine to protect against the potentially deadly bird flu.
Research
Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care WorkersThe bacille Calmette-Guérin (BCG) vaccine has immunomodulatory "off-target" effects that have been hypothesized to protect against coronavirus disease 2019.
Research
Mandating COVID-19 vaccinations for children: Attitudes of Western Australian parentsAustralian governments have used vaccine mandates to drive high uptake of routine childhood vaccines and adult Coronavirus Disease 2019 (COVID-19) and influenza vaccines. We sought to understand the attitudes of Western Australian parents regarding mandating COVID-19 vaccines for children, interviewing 44 parents of children aged up to 18 years between May and December 2021. Transcripts were analysed to ascertain parents' attitudes and sources of reasoning.
Research
Lessons learnt from influenza vaccination in immunocompromised children undergoing treatment for cancerInfluenza infection contributes substantially to global morbidity and mortality, with children undergoing treatment for cancer among the most vulnerable due to immunosuppression associated with disease and treatment. However, influenza remains one of the most common vaccine-preventable diseases.
Research
Tracking of activated cTfh cells following sequential influenza vaccinations reveals transcriptional profile of clonotypes driving a vaccine-induced immune responseA vaccine against influenza is available seasonally but is not 100% effective. A predictor of successful seroconversion in adults is an increase in activated circulating T follicular helper (cTfh) cells after vaccination. However, the impact of repeated annual vaccinations on long-term protection and seasonal vaccine efficacy remains unclear.