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Research

Lung function in African infants in the Drakenstein child health study impact of lower respiratory tract illness

Early life lower respiratory tract illness impairs lung function at 1 year, independent of baseline lung function

Research

Key paediatric messages from the 2016 european respiratory society international congress

In this article, the Group Chairs of the Paediatric Assembly of the European Respiratory Society (ERS) highlight some of the most interesting abstracts presented at the 2016 ERS International Congress, which was held in London.

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Meningococcal serogroup B-specific responses after vaccination with bivalent rLP2086

Assessment of the persistence of bactericidal antibodies up to 4 years after a three-dose schedule of bivalent rLP2086

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Host–Parasite Relationships and Life Histories of Trypanosomes in Australia

We review what is known about the diversity, life histories, host-parasite interactions and evolutionary relationships of trypanosomes in Australian wildlife

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The impact of expanding access to early childhood education services in rural Indonesia.

This article examines the relationship between preschool quality and children’s early development in a sample of over 7900 children enrolled in 578 preschools in rural Indonesia.

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Facilitating Empowerment and Self-Determination Through Participatory Action Research

This article details the application of the participatory action research approach by the National Empowerment Project, Aboriginal community-based researchers.

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Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical Research

We outline three scenarios from across the health spectrum where issues with health informatics are exemplified.

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Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung

We aimed to delineate the effects of LPS and AMP on airway inflammation, and potential contribution to airway disease by measuring airway inflammatory responses

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CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis

CFTR-dependent imbalance of macrophage phenotypes and functions could contribute to the exaggerated inflammatory response seen in CF lung disease

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PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

Our results reveal long-lasting changes to progenitor cells of monocytes/macrophages by a 2-hour dimethyl PGE2 pulse that, in turn, limits the migration of their daughter cells to chemoattractants and inflammatory mediators.