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Research

Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children

Bacterial airway microbiome is highly variable in early life and its role in wheeze remains less clear than viral influences

Research

Using pneumococcal carriage studies to monitor vaccine impact in low- and middle-income countries

We review the role of pneumococcal carriage studies for the evaluation of PCVs in LMICs and discuss optimal methods for conducting these studies

Research

A framework for the management of the pediatric airway

A simple, time critical, and pediatric-specific airway management approach will help to reduce airway-related pediatric morbidity and mortality

Research

Evidence of functional cell-mediated immune responses to nontypeable Haemophilus influenzae in otitis-prone children

These data provide evidence that otitis-prone children do not have impaired functional cell mediated immunity

Research

Development of an opsonophagocytic killing assay for Group A Streptococcus

Group A Streptococcus (GAS) or Streptococcus pyogenes is responsible for an estimated 500,000 deaths worldwide each year.

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Paediatric antimicrobial stewardship and safe prescribing: An assessment of medical staff knowledge and behaviour

Participants demonstrated a good understanding of safe prescribing and antimicrobial stewardship

Research

Can a simple dietary index derived from a sub-set of questionnaire items assess diet quality in a sample of australian adults?

This study describes a method that was used to develop a simple index for ranking individuals according to their diet quality in a longitudinal study

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Immunological processes driving IgE sensitisation and disease development in males and females

In this review, we discuss recent mechanistic studies casting further light on how the expression of sex hormones may influence the innate and adaptive immune system

Research

Persistent induction of goblet cell differentiation in the airways: Therapeutic approaches

Here we review the current knowledge of key molecular pathways that are dysregulated during persistent goblet cell differentiation