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The application of environmental health assessment strategies to detect Streptococcus pyogenes in Kimberley school classrooms

Children spend almost one-third of their waking hours at school. Streptococcus pyogenes (Strep A) is a common childhood bacterial infection that can progress to causing serious disease. We aimed to detect Strep A in classrooms by using environmental settle plates and swabbing of high-touch surfaces in two remote schools in the Kimberley, Western Australia.

Ion channel modulator DPI-201-106 significantly enhances antitumor activity of DNA damage response inhibitors in glioblastoma

Glioblastoma, a lethal high-grade glioma, has not seen improvements in clinical outcomes in nearly 30 years. Ion channels are increasingly associated with tumorigenesis, and there are hundreds of brain-penetrant drugs that inhibit ion channels, representing an untapped therapeutic resource. The aim of this exploratory drug study was to screen an ion channel drug library against patient-derived glioblastoma cells to identify new treatments for brain cancer. 

Morbidity of Scabies in Resource-Limited Countries: Rheumatic Heart Disease (RHD) and Post-Streptococcal Glomerulonephritis (APSGN)

Scabies is one of the world’s most prevalent diseases, with approximately 147 million cases at any one time and an estimated annual incidence of 455 million new episodes. Although Group A streptococcal (GAS) pharyngitis has long been implicated in the pathogenesis of acute rheumatic fever (ARF) and subsequent rheumatic heart disease (RHD), impetigo caused by GAS has recently been postulated as a link between scabies and the pathogenesis of ARF.

Focused Therapy Programs

Find out about the range of Focused Therapy programs on offer at CliniKids.

Custom Medicine for Kids

Thanks to an enabling donation from the Stan Perron Charitable Foundation, The Kids Research Institute Australia is home to one of the first paediatric personalised medicine research centres in the world.

Ngulluk Koolunga Ngulluk Koort

The Ngulluk Koolunga Ngulluk Koort (Our Children, Our Heart) Project grew out of a bold vision to harness the wisdom of Aboriginal Elders to improve outcomes for Aboriginal children, producing a suite of Elder-led, culturally appropriate and empowering initiatives that are making a difference.

Supporting siblings of autistic children

In this new blog, Senior Clinical Psychologist Rebecca Eaton offers families advice on how to support siblings of autistic children.

Bathtime can mean more than just getting clean!

In this new blog, Speech Pathology Lead Aria May explains how bathtime is a great opportunity to support social communication with your child.

Landmark flu decision set to save kids’ lives

For the first time this year, all Australian babies and children aged six months to four years will be entitled to have a free influenza vaccination.