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Towards the development of an integrative, evidence-based suite of indicators for the prediction of outcome following mild traumatic brain injuryPerformance on neuropsychological measures may be useful for predicting persisting post-concussion symptoms
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Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma modelWe established a pipeline to assess the effects of epigenetic modifiers on CD8+ T cell proliferation, differentiation, and efficacy in a preclinical melanoma model
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Using pneumococcal carriage studies to monitor vaccine impact in low- and middle-income countriesWe review the role of pneumococcal carriage studies for the evaluation of PCVs in LMICs and discuss optimal methods for conducting these studies
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A framework for the management of the pediatric airwayA simple, time critical, and pediatric-specific airway management approach will help to reduce airway-related pediatric morbidity and mortality
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Early life determinants of health: Invest early to break the cycle of long-term disadvantage in neurodevelopmental disordersThis chapter discusses the importance of investment in early life determinants of health to break the cycle of long-term disadvantage. This chapter addresses these issues while focussing on neurodevelopmental disorders and their related mental health concerns as the targets at the centre of a biopsychosocial transformation of the health system.
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Evolving Trends of Gastrostomy Insertion Within a Pediatric PopulationNew gastrostomy insertion among children who require long-term enteral feeding support increased over the study period
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Assessment of on-time vaccination coverage in population subgroups: A record linkage cohort studyOn-time coverage of the 2-4-6 month schedule is only 50-60% across specific population subgroups representing a significant avoidable public health risk
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Development of an opsonophagocytic killing assay for Group A StreptococcusGroup A Streptococcus (GAS) or Streptococcus pyogenes is responsible for an estimated 500,000 deaths worldwide each year.
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Food environments and dietary intakes among adults: Does the type of spatial exposure measurement matter? A systematic reviewAvailability measures may produce significant and greater effect sizes than accessibility measures
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Immunological processes driving IgE sensitisation and disease development in males and femalesIn this review, we discuss recent mechanistic studies casting further light on how the expression of sex hormones may influence the innate and adaptive immune system